Here are the supporting materials for Episode 22 'Deep Dive Into The Look Ahead Study:Face-Saving Through Shifting Goalposts'


The Look AHEAD Study aimed to see whether intentional weight loss resulted in reduced chance of death. After 9 years they found it didn’t but that hasn’t stopped them singing the praises of weight loss. This episode unpacks why. 


Learning goals:

  • Describe the Look AHEAD trial
  • Appreciate the process involved in calculating how many people are needed in a study to be able to confirm or reject a hypothesis (power calculation)
  • Recognise the shift from hard outcome endpoints (disease/death) to weight loss outcomes (surrogate markers/risk factors) and understand the circumstances that drive this phenomenon.


This download includes:

- Learning outcomes

- Links to key articles

- Further reading

- Summary information

- Self-Test Quiz (with answers!)

Episode 22 Supporting Materials

  • Copyright © 2019 by Fiona Willer. All rights reserved.

    This document or any portion thereof may not be reproduced or used in any manner whatsoever without the express written permission of the publisher except for the use of brief quotations where attributed appropriately.

    These materials are for individual use and must not be shared.

    The materials provided are for educational purposes only, and designed to enhance your research appraisal skills and weight-related knowledge.  The education provided is intended to broaden the knowledge of professionals but does not constitute professional training or licence any professional to practice outside their official scope of practice.  ‘Fiona Willer’, ‘Health Not Diets’ and ‘Unpacking Weight Science’ and their facilitators do not accept any liability for any injury, loss or damage incurred by use of or reliance on the information provided herein.

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